- Savonarola, Girolamo, 1452-14981
- Saxo, Andreas1
- Scala, Giovanni1
- Scalandroni family1
- Schmalkaldic War (1546-1547)1
- Seccrani, Marco1
- Seccrani, Parrino1
- Seneca, Lucius Annaeus, approximately 4 B.C.-65 A.D.1
- Sepúlveda, Juan Ginés de, 1490-15731
- Sermini, Baldassare Girolamo1
- Sermini, Giovanni1
- Sermons, English1
- Sermons, Latin1
- Sermons, Spanish1
- Shelomoh ben Yeshuʹa, 16th century1
- Siege of Istanbul (Istanbul, Turkey : 1453)1
- Siena (Italy). Balia1
- Sigismund II Augustus, King of Poland, 1520-15721
- Slavery1
- Social conditions1