- Seccrani, Parrino1
- Seneca, Lucius Annaeus, approximately 4 B.C.-65 A.D.1
- Sepulchral monuments1
- Sepúlveda, Juan Ginés de, 1490-15731
- Serfdom1
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- Settala, Ludovico, 1552?-16331
- Siege of Istanbul (Istanbul, Turkey : 1453)1
- Siege warfare1
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- Sigismund II Augustus, King of Poland, 1520-15721
- Slavery1
- Soderini, Giovanni di Luigi1
- Songs, Italian1
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- Soria (ship)1